The Notch pathway is integrated into numerous developmental processes and therefore is fine-tuned on many levels, including receptor production, endocytosis, Christmas for our Facebook friends and degradation.Notch is further characterized by a twofold relationship with its Delta-Serrate (DSL) ligands, as ligands from opposing cells (trans-ligands)

Establishing if species contractions were the result of natural phenomena or human induced landscape changes is essential for managing natural populations.Fishers (Martes pennanti) in California occur in two geographically and genetically isolated populations in the northwestern mountains and southern Sierra Nevada.Their isolation is hypothesized t

Abstract Background Accelerated partial breast irradiation (APBI) is an accepted treatment option for early breast cancer.Treatment delivered on the Magnetic Resonance Knitwear integrated Linear Accelerator (MRL) provides the added assurance of improved soft tissue visibility, important in the delivery of APBI.This technique can be delivered in bot

High-speed rotors on gas foil bearings (GFBs) are applications of increasing interest due to their potential to increase the Beauty power-toweight ratio in machines and also formulate oil-free design solutions.The gas lubrication principles render lower (compared to oil) power loss and increase the threshold speed of instability in rotating systems

Lubes A considerable difference between experimental and theoretical results has been observed in the studies of segmented thermoelectric generators (STEGs).Because of simplicity, the approximate methods are widely used for design and optimization of the STEGs.This study is focused on employment of exact method for design and optimization of STEGs